<?xml version="1.0" encoding="UTF-8"?>
<!--REG30 V1.0 (16-10-2025)-->
<xbrli:xbrl xmlns:in-capmkt="http://www.sebi.gov.in/xbrl/2025-08-31/in-capmkt" xmlns:in-capmkt-ent="http://www.sebi.gov.in/xbrl/Regulation_30_Restructuring/2025-08-31/in-capmkt/in-capmkt-ent" xmlns:in-capmkt-roles="http://www.sebi.gov.in/xbrl/Regulation_30_Restructuring/2025-08-31/in-capmkt-roles" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:net="http://www.xbrl.org/2009/role/net" xmlns:num="http://www.xbrl.org/dtr/type/numeric" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:negated="http://www.xbrl.org/2009/role/negated" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xl="http://www.xbrl.org/2003/XLink"><link:schemaRef xlink:type="simple" xlink:href="in-capmkt-ent-2025-08-31.xsd"/><xbrli:context id="OneI"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">512529</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2026-09-08</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="OneD"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">512529</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2026-09-08</xbrli:startDate><xbrli:endDate>2026-09-08</xbrli:endDate></xbrli:period></xbrli:context><in-capmkt:ScripCode contextRef="OneI">512529</in-capmkt:ScripCode><in-capmkt:NameOfTheCompany contextRef="OneI">VIYASH SCIENTIFIC LIMITED</in-capmkt:NameOfTheCompany><in-capmkt:NSESymbol contextRef="OneI">VIYASH</in-capmkt:NSESymbol><in-capmkt:MSEISymbol contextRef="OneI">NOTLISTED</in-capmkt:MSEISymbol><in-capmkt:ISIN contextRef="OneI">INE807F01027</in-capmkt:ISIN><in-capmkt:TypeOfAnnouncementPertainingToRegulation30Restructuring contextRef="OneD">Update</in-capmkt:TypeOfAnnouncementPertainingToRegulation30Restructuring><in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfBoardMeeting contextRef="OneD">false</in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfBoardMeeting><in-capmkt:DateOfOccurrenceOfEvent contextRef="OneI">2026-09-07</in-capmkt:DateOfOccurrenceOfEvent><in-capmkt:TimeOfOccurrenceOfEvent contextRef="OneD">23:59:00</in-capmkt:TimeOfOccurrenceOfEvent><in-capmkt:DateOfInitialAnnouncement contextRef="OneI">2026-06-08</in-capmkt:DateOfInitialAnnouncement><in-capmkt:DateOfLatestAnnouncement contextRef="OneI">2026-07-21</in-capmkt:DateOfLatestAnnouncement><in-capmkt:DateOfReport contextRef="OneI">2026-09-08</in-capmkt:DateOfReport><in-capmkt:UpdateForTheEvent contextRef="OneD">Acquisition (including agreement to acquire)</in-capmkt:UpdateForTheEvent><in-capmkt:BriefDetailsOfInitialAnnouncement contextRef="OneI">In continuation of our earlier disclosures dated June 8, 2026 and July 21, 2026 (collectively referred to as the “Disclosures”) regarding the proposed acquisition of 100% shareholding in BioForLife Italia S.r.l., Milan, Italy by Alivira Animal Health Limited, Ireland, a step-down wholly owned subsidiary of Viyash Scientific Limited, we wish to inform you that the requisite approval in connection with the applicable Italian FDI / Golden Power regulations has been received from the relevant Italian authorities. Further, taking into account the remaining customary closing formalities and closing conditions, the expected timeline for completion of the transaction has been revised, and the transaction is now expected to be completed within two months from the date of this intimation.</in-capmkt:BriefDetailsOfInitialAnnouncement><in-capmkt:ReasonForUpdate contextRef="OneD">Others</in-capmkt:ReasonForUpdate><in-capmkt:OtherUpdates contextRef="OneI">In continuation of our earlier disclosures dated June 8, 2026 and July 21, 2026 (collectively referred to as the “Disclosures”) regarding the proposed acquisition of 100% shareholding in BioForLife Italia S.r.l., Milan, Italy by Alivira Animal Health Limited, Ireland, a step-down wholly owned subsidiary of Viyash Scientific Limited, we wish to inform you that the requisite approval in connection with the applicable Italian FDI / Golden Power regulations has been received from the relevant Italian authorities. Further, taking into account the remaining customary closing formalities and closing conditions, the expected timeline for completion of the transaction has been revised, and the transaction is now expected to be completed within two months from the date of this intimation.</in-capmkt:OtherUpdates></xbrli:xbrl>
