<?xml version="1.0" encoding="UTF-8"?>
<!--REG30PARAB V1.0 (01-06-2026)-->
<xbrli:xbrl xmlns:in-capmkt="http://www.sebi.gov.in/xbrl/2026-04-30/in-capmkt" xmlns:in-capmkt-ent="http://www.sebi.gov.in/xbrl/Regulation_30_Para_B_Of_Part_A_Of_Schedule_III/2026-04-30/in-capmkt/in-capmkt-ent" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:in-capmkt-types="http://www.sebi.gov.in/xbrl/2026-04-30/in-capmkt-types" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:net="http://www.xbrl.org/2009/role/net" xmlns:num="http://www.xbrl.org/dtr/type/numeric" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:negated="http://www.xbrl.org/2009/role/negated" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xl="http://www.w3.org/1999/xlink"><link:schemaRef xlink:type="simple" xlink:href="in-capmkt-ent-2026-04-30.xsd"/><xbrli:context id="MainI"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">532843</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2026-09-16</xbrli:instant></xbrli:period></xbrli:context><xbrli:context id="I_ArrangementsForStrategicOrTechnicalOrManufacturingOrMarketingTieUp"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">532843</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2026-09-16</xbrli:instant></xbrli:period><xbrli:scenario><xbrldi:explicitMember dimension="in-capmkt:SubTypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIIIAxis">in-capmkt:ArrangementsForStrategicOrTechnicalOrManufacturingOrMarketingTieUpMember</xbrldi:explicitMember></xbrli:scenario></xbrli:context><in-capmkt:NSESymbol contextRef="MainI">FORTIS</in-capmkt:NSESymbol><in-capmkt:NameOfTheCompany contextRef="MainI">Fortis Healthcare Limited</in-capmkt:NameOfTheCompany><in-capmkt:ScripCode contextRef="MainI">532843</in-capmkt:ScripCode><in-capmkt:MSEISymbol contextRef="MainI">NOTLISTED</in-capmkt:MSEISymbol><in-capmkt:ISIN contextRef="MainI">INE061F01013</in-capmkt:ISIN><in-capmkt:TypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII contextRef="MainI">Arrangement/Adoption of new line/Closure of operations (Sub-para 2-Para B)</in-capmkt:TypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII><in-capmkt:SubTypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII contextRef="I_ArrangementsForStrategicOrTechnicalOrManufacturingOrMarketingTieUp">Arrangements for strategic, technical, manufacturing, or marketing tie up</in-capmkt:SubTypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII><in-capmkt:TypeOfAnnouncementAsPerRegulation30ParaBOfPartAOfScheduleIII contextRef="MainI">New</in-capmkt:TypeOfAnnouncementAsPerRegulation30ParaBOfPartAOfScheduleIII><in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfTheBoardMeeting contextRef="MainI">false</in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfTheBoardMeeting><in-capmkt:DateOfOccurrenceOfEventOrInformation contextRef="MainI">2026-09-16</in-capmkt:DateOfOccurrenceOfEventOrInformation><in-capmkt:TimeOfOccurrenceOfEventOrInformation contextRef="MainI">12:55:00</in-capmkt:TimeOfOccurrenceOfEventOrInformation><in-capmkt:DateOfReport contextRef="MainI">2026-09-16</in-capmkt:DateOfReport><in-capmkt:TypeOfArrangement contextRef="MainI">Agreement</in-capmkt:TypeOfArrangement><in-capmkt:NameOfEntitiesWithWhomAgreementOrJointVentureIsSigned contextRef="MainI">Seth Sunder Lal Jain Charitable Eye Hospital, a society organized under the Society Registration Act, 1860 (Punjab Amendment) (“SLJ Society”)</in-capmkt:NameOfEntitiesWithWhomAgreementOrJointVentureIsSigned><in-capmkt:AreaOfAgreementOrJointVenture contextRef="MainI">Healthcare services agreement (“Healthcare Services Agreement” or “HSA”), loan agreement (“Loan Agreement”) and certain other ancillary agreements</in-capmkt:AreaOfAgreementOrJointVenture><in-capmkt:WhetherArrangementIsDomesticOrInternational contextRef="MainI">Domestic</in-capmkt:WhetherArrangementIsDomesticOrInternational><in-capmkt:ShareExchangeRatioOrJointVentureRatio contextRef="MainI">Not applicable</in-capmkt:ShareExchangeRatioOrJointVentureRatio><in-capmkt:ScopeOfBusinessOperationOfAgreementOrJointVenture contextRef="MainI">Pursuant to the Healthcare Services Agreement and the ancillary agreements thereto, SLJ Society has granted exclusive right to Fortis Hospotel Limited, a wholly owned subsidiary of the Company (“FHTL”) to provide healthcare and medical services at the hospital to be constructed and operated by SLJ Society at Ashok Vihar, Delhi – 110052 (“Hospital”) in accordance with the terms thereof. 

The Hospital shall be owned, operated and managed by SLJ Society and FHTL shall provide healthcare and medical services at the Hospital pursuant to the terms of the Healthcare Services Agreement. The land, building, and related civil infrastructure, together with certain medical infrastructure required for the Hospital, shall also be owned and developed by SLJ Society. 

Pursuant to the Loan Agreement and the ancillary agreements thereto, FHTL has agreed to provide a loan to SLJ Society up to an amount of INR 5,67,00,00,000 (Indian Rupees Five Hundred Sixty Seven Crores only) for the purposes of, inter alia, construction, upgradation and operation of the Hospital of SLJ Society. The loan amount will be disbursed in multiple tranches over the next 3-4 years basis  construction progress and as per terms mutually agreed. In furtherance of loan, SLJ Society has created appropriate security in favour of FHTL.
</in-capmkt:ScopeOfBusinessOperationOfAgreementOrJointVenture><in-capmkt:DetailsOfConsiderationPaidOrReceivedInAgreementOrJointVenture contextRef="MainI">Under the Healthcare Services Agreement, FHTL shall be entitled to a service fee which shall be certain percentage of the revenue generated by the Hospital operated by SLJ Society.

As security for the performance by FHTL of its obligations under the Healthcare Services Agreement, FHTL has provided an interest free refundable security deposit to SLJ Society.

With respect to the loan, FHTL will be entitled to receive an interest as per the Loan Agreement.</in-capmkt:DetailsOfConsiderationPaidOrReceivedInAgreementOrJointVenture><in-capmkt:SignificantTermsAndConditionsOfAgreementOrJointVenture contextRef="MainI">Pursuant to the Healthcare Services Agreement, SLJ Society has granted long term exclusive right to FHTL to provide healthcare services at the Hospital of SLJ Society. The HSA has a committed term of 29 years, with an option to extend for further period on mutually agreed terms.</in-capmkt:SignificantTermsAndConditionsOfAgreementOrJointVenture><in-capmkt:WhetherTheAcquisitionWouldFallWithinRelatedPartyTransactions contextRef="MainI">false</in-capmkt:WhetherTheAcquisitionWouldFallWithinRelatedPartyTransactions><in-capmkt:SizeOfEntityInArrangement contextRef="MainI">Not applicable</in-capmkt:SizeOfEntityInArrangement><in-capmkt:RationaleAndExpectedBenefitOfArrangement contextRef="MainI">The proposed collaboration with SLJ Society through the Healthcare Services Agreement is aimed at strengthening healthcare access in North-West Delhi, an underserved micro-market characterised by a dense residential population. While the hospital will be owned, operated and managed by SLJ Society, Fortis will provide healthcare services under the agreement.</in-capmkt:RationaleAndExpectedBenefitOfArrangement></xbrli:xbrl>
