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<!--REG30PARAB V1.0 (01-06-2026)-->
<xbrli:xbrl xmlns:in-capmkt="http://www.sebi.gov.in/xbrl/2026-04-30/in-capmkt" xmlns:in-capmkt-ent="http://www.sebi.gov.in/xbrl/Regulation_30_Para_B_Of_Part_A_Of_Schedule_III/2026-04-30/in-capmkt/in-capmkt-ent" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:in-capmkt-types="http://www.sebi.gov.in/xbrl/2026-04-30/in-capmkt-types" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:net="http://www.xbrl.org/2009/role/net" xmlns:num="http://www.xbrl.org/dtr/type/numeric" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:negated="http://www.xbrl.org/2009/role/negated" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xl="http://www.w3.org/1999/xlink"><link:schemaRef xlink:type="simple" xlink:href="in-capmkt-ent-2026-04-30.xsd"/><xbrli:context id="MainI"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">500306</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:instant>2026-10-22</xbrli:instant></xbrli:period></xbrli:context><in-capmkt:NSESymbol contextRef="MainI">JAYKAY</in-capmkt:NSESymbol><in-capmkt:NameOfTheCompany contextRef="MainI">JAYKAY ENTERPRISES LIMITED</in-capmkt:NameOfTheCompany><in-capmkt:ScripCode contextRef="MainI">500306</in-capmkt:ScripCode><in-capmkt:MSEISymbol contextRef="MainI">NA</in-capmkt:MSEISymbol><in-capmkt:ISIN contextRef="MainI">INE903A01025</in-capmkt:ISIN><in-capmkt:TypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII contextRef="MainI">Key licenses or regulatory approvals (Sub-para 12-Para B)</in-capmkt:TypeOfEventAsPerRegulation30ParaBOfPartAOfScheduleIII><in-capmkt:TypeOfAnnouncementAsPerRegulation30ParaBOfPartAOfScheduleIII contextRef="MainI">New</in-capmkt:TypeOfAnnouncementAsPerRegulation30ParaBOfPartAOfScheduleIII><in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfTheBoardMeeting contextRef="MainI">false</in-capmkt:WhetherEventOrInformationDisclosedIsAnOutcomeOfTheBoardMeeting><in-capmkt:DateOfOccurrenceOfEventOrInformation contextRef="MainI">2026-10-21</in-capmkt:DateOfOccurrenceOfEventOrInformation><in-capmkt:TimeOfOccurrenceOfEventOrInformation contextRef="MainI">17:49:00</in-capmkt:TimeOfOccurrenceOfEventOrInformation><in-capmkt:DateOfReport contextRef="MainI">2026-10-22</in-capmkt:DateOfReport><in-capmkt:EventTypeOfKeyLicenseOrRegulatoryApproval contextRef="MainI">Key licenses</in-capmkt:EventTypeOfKeyLicenseOrRegulatoryApproval><in-capmkt:StageOfDisclosureOfKeyLicenseOrRegulatoryApproval contextRef="MainI">Granting</in-capmkt:StageOfDisclosureOfKeyLicenseOrRegulatoryApproval><in-capmkt:NameOfRegulatoryOrLicensingAuthority contextRef="MainI">Central Drugs Standard Control Organisation (CDSCO), Directorate General of Health Services, Ministry of Health &amp; Family Welfare, Government of India</in-capmkt:NameOfRegulatoryOrLicensingAuthority><in-capmkt:BriefDetailsOfApprovalOrLicenseObtainedOrWithdrawnOrSurrendered contextRef="MainI">Licence to Manufacture for Sale or for Distribution of Class C or Class D Medical Devices, bearing Licence No. MFG/MD/2026/000784 dated
21 October 2026, issued under the Medical Devices Rules, 2017.The licence covers the following eight categories of advanced medical implants:
1. Lattice Acetabular Cups: for complex hip revision surgeries and reconstruction of severe acetabular bone defects.
2. Lattice Cone Acetabular Cups: for complex hip revision surgeries and reconstruction of severe acetabular bone defects.
3. Lattice Buttress Implants: to provide structural support during revision total hip arthroplasty.
4. Lattice Shim Implants: for structural gap-filling and angular adjustment in hip reconstruction procedures.
5. Lattice Cage Constructs: for reconstruction of severe acetabular bone defects in complex primary or revision hip replacement procedures.
6. Lattice TLIF Spinal Implants: implants used in transforaminal lumbar interbody fusion procedures.
7. Lattice PLIF Spinal Implants: implants used in posterior lumbar interbody fusion procedures.
8. Lattice Shells and Wedges: for augmentation, reconstruction and reinforcement of acetabular bone during complex hip replacement procedures.</in-capmkt:BriefDetailsOfApprovalOrLicenseObtainedOrWithdrawnOrSurrendered><in-capmkt:ImpactOrRelevanceOfApprovalOrLicenseToListedEntity contextRef="MainI">The receipt of this licence marks an important regulatory milestone for JK Digital &amp; Advance Systems Private Limited and establishes the regulatory authorisation to manufacture the specified specialised orthopaedic and spinal implant products, subject to the terms and conditions of the licence and applicable regulatory requirements.
This development strengthens the presence of Jaykay Enterprises Limited in the specialised medical devices segment and provides a regulatory foundation for pursuing opportunities in advanced orthopaedic and spinal implant solutions.</in-capmkt:ImpactOrRelevanceOfApprovalOrLicenseToListedEntity><in-capmkt:ReasonsForActionOfGrantingOrWithdrawalOrSurrenderOrCancellationOrSuspensionOfKeyLicensesOrRegulatoryApprovals contextRef="MainI">JK Digital &amp; Advance Systems Private Limited (“JK Digital”), a wholly owned subsidiary of Jaykay Enterprises Limited (the “Company”), has received a Licence to Manufacture for Sale or for Distribution of Class C or Class D Medical Devices, bearing Licence No. MFG/MD/2026/000784 dated 21 October 2026, issued by the Central Drugs Standard Control Organisation (CDSCO), Directorate General of Health Services, Ministry of Health &amp; Family Welfare, Government of India, under the Medical Devices Rules, 2017.</in-capmkt:ReasonsForActionOfGrantingOrWithdrawalOrSurrenderOrCancellationOrSuspensionOfKeyLicensesOrRegulatoryApprovals><in-capmkt:EstimatedImpactOfKeyLicenseOrRegulatoryApprovalOnListedEntity contextRef="MainI">This development strengthens the presence of Jaykay Enterprises Limited in the specialised medical devices segment and provides a regulatory foundation for pursuing opportunities in advanced orthopaedic and spinal implant solutions.</in-capmkt:EstimatedImpactOfKeyLicenseOrRegulatoryApprovalOnListedEntity><in-capmkt:PeriodOfKeyLicenseOrRegulatoryApproval contextRef="MainI">Lifetime</in-capmkt:PeriodOfKeyLicenseOrRegulatoryApproval><in-capmkt:ActualImpactOfKeyLicenseOrRegulatoryApprovalOnListedEntity contextRef="MainI">This development strengthens the presence of Jaykay Enterprises Limited in the specialised medical devices segment and provides a regulatory foundation for pursuing opportunities in advanced orthopaedic and spinal implant solutions.</in-capmkt:ActualImpactOfKeyLicenseOrRegulatoryApprovalOnListedEntity><in-capmkt:CorrectiveActionsTakenByTheListedEntityPursuantToTheWithdrawalOrSurrenderOrCancellationOrSuspensionOfKeyLicensesOrRegulatoryApprovals contextRef="MainI">NA</in-capmkt:CorrectiveActionsTakenByTheListedEntityPursuantToTheWithdrawalOrSurrenderOrCancellationOrSuspensionOfKeyLicensesOrRegulatoryApprovals></xbrli:xbrl>