<?xml version="1.0" encoding="UTF-8"?>
<xbrli:xbrl xmlns:in-capmkt="https://www.sebi.gov.in/xbrl/2023-05-31/in-capmkt" xmlns:in-capmkt-ent="https://www.sebi.gov.in/xbrl/Prior_Intimation_Of_Board_Meeting/2023-05-31/in-capmkt/in-capmkt-ent" xmlns:in-capmkt-roles="https://www.sebi.gov.in/xbrl/Prior_Intimation_Of_Board_Meeting/2023-05-31/in-capmkt-roles" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:in-capmkt-type="https://www.sebi.gov.in/xbrl/2023-05-31/in-capmkt-types" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:net="http://www.xbrl.org/2009/role/net" xmlns:num="http://www.xbrl.org/dtr/type/numeric" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:negated="http://www.xbrl.org/2009/role/negated" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:xl="http://www.xbrl.org/2003/XLink">
<link:schemaRef xlink:type="simple" xlink:href="in-capmkt-ent-2023-05-31.xsd"/>

<xbrli:unit id="INR"><xbrli:measure>iso4217:INR</xbrli:measure></xbrli:unit><xbrli:unit id="pure"><xbrli:measure>xbrli:pure</xbrli:measure></xbrli:unit><xbrli:unit id="shares"><xbrli:measure>xbrli:shares</xbrli:measure></xbrli:unit><xbrli:unit id="INRPerShare"><xbrli:divide><xbrli:unitNumerator><xbrli:measure>iso4217:INR</xbrli:measure></xbrli:unitNumerator><xbrli:unitDenominator><xbrli:measure>xbrli:shares</xbrli:measure></xbrli:unitDenominator></xbrli:divide></xbrli:unit>
<in-capmkt:NSESymbol contextRef="OneI">BLISSGVS</in-capmkt:NSESymbol>
<in-capmkt:NameOfTheCompany contextRef="OneI">BLISS GVS PHARMA LIMITED</in-capmkt:NameOfTheCompany>
<in-capmkt:ISIN contextRef="OneI">INE416D01022</in-capmkt:ISIN>
<in-capmkt:TypeOfMeeting contextRef="OneI">Board Meeting</in-capmkt:TypeOfMeeting>
<in-capmkt:TypeOfIntimation contextRef="OneD">New</in-capmkt:TypeOfIntimation>
<in-capmkt:DateOfProposedMeeting contextRef="OneD">2026-02-10</in-capmkt:DateOfProposedMeeting>
<in-capmkt:WhetherTradingWindowIsClosed contextRef="OneD">Yes</in-capmkt:WhetherTradingWindowIsClosed>
<in-capmkt:DateOfStartOfTradingWindowClosure contextRef="OneI">2026-01-01</in-capmkt:DateOfStartOfTradingWindowClosure>
<in-capmkt:DetailsOfDateOfEndOfTradingWindowClosure contextRef="OneI">2026-02-12</in-capmkt:DetailsOfDateOfEndOfTradingWindowClosure>
<in-capmkt:Agenda1 contextRef="OneD">Dividend</in-capmkt:Agenda1>
<in-capmkt:Agenda2 contextRef="OneD">Financial results</in-capmkt:Agenda2>
<in-capmkt:WhetherResultsAreAuditedOrUnaudited contextRef="OneD">Unaudited</in-capmkt:WhetherResultsAreAuditedOrUnaudited>
<in-capmkt:NatureOfReportStandaloneConsolidated contextRef="OneD">Standalone And Consolidated</in-capmkt:NatureOfReportStandaloneConsolidated>
<in-capmkt:ReportingPeriodType contextRef="OneD">Quarterly</in-capmkt:ReportingPeriodType>
<in-capmkt:MonthOfPeriodEnded contextRef="OneD">December</in-capmkt:MonthOfPeriodEnded>
<in-capmkt:YearOfPeriodEnded contextRef="OneI" unitRef="INR" decimals="0">2025</in-capmkt:YearOfPeriodEnded>
<in-capmkt:TypeOfDividend contextRef="OneD">Interim</in-capmkt:TypeOfDividend>
<in-capmkt:RemarksWebsiteDissemination contextRef="OneI">We wish to inform you that a meeting of the Board of Directors of the Company is scheduled to be held on Tuesday, February 10, 2026, at the registered office of the Company, inter alia, to consider and approve the Unaudited Standalone and Consolidated Financial Results of the Company for the quarter and nine months ended December 31, 2025 and Interim Dividend, if any, for the financial year 2025-2026.</in-capmkt:RemarksWebsiteDissemination>
</xbrli:xbrl>