<?xml version="1.0" encoding="UTF-8" standalone="no"?><!--IFIndAs V2.1 (26-06-2026)--><xbrli:xbrl xmlns:xbrli="http://www.xbrl.org/2003/instance" xmlns:in-capmkt="http://www.sebi.gov.in/xbrl/2026-01-31/in-capmkt" xmlns:in-capmkt-ent="http://www.sebi.gov.in/xbrl/IntegratedFinance_IndAS/2026-01-31/in-capmkt/in-capmkt-ent" xmlns:in-capmkt-roles="http://www.sebi.gov.in/xbrl/IntegratedFinance_IndAS/2026-01-31/in-capmkt-roles" xmlns:in-capmkt-types="http://www.sebi.gov.in/xbrl/2026-01-31/in-capmkt-types" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:negated="http://www.xbrl.org/2009/role/negated" xmlns:net="http://www.xbrl.org/2009/role/net" xmlns:nonnum="http://www.xbrl.org/dtr/type/non-numeric" xmlns:num="http://www.xbrl.org/dtr/type/numeric" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xmlns:xl="http://www.xbrl.org/2003/XLink" xmlns:xlink="http://www.w3.org/1999/xlink"><link:schemaRef xlink:href="in-capmkt-ent-2026-01-31.xsd" xlink:type="simple"/><xbrli:context id="OneD"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">500830</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2026-04-01</xbrli:startDate><xbrli:endDate>2026-06-30</xbrli:endDate></xbrli:period></xbrli:context><xbrli:context id="OneExpenses1D"><xbrli:entity><xbrli:identifier scheme="http://www.sebi.gov.in/in-capmkt/ScripCode">500830</xbrli:identifier></xbrli:entity><xbrli:period><xbrli:startDate>2026-04-01</xbrli:startDate><xbrli:endDate>2026-06-30</xbrli:endDate></xbrli:period><xbrli:scenario><xbrldi:explicitMember dimension="in-capmkt:DetailsOfOtherExpensesAxis">in-capmkt:OtherExpenses1Member</xbrldi:explicitMember></xbrli:scenario></xbrli:context><xbrli:context id="OneExpenses2D"><xbrli:entity><xbrli:identifier 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contextRef="OneD">INE259A01022</in-capmkt:ISIN><in-capmkt:NameOfTheCompany contextRef="OneD">Colgate Palmolive India Limited</in-capmkt:NameOfTheCompany><in-capmkt:TypeOfCompany contextRef="OneD">Main Board</in-capmkt:TypeOfCompany><in-capmkt:ClassOfSecurity contextRef="OneD">Equity</in-capmkt:ClassOfSecurity><in-capmkt:DateOfStartOfFinancialYear contextRef="OneD">2026-04-01</in-capmkt:DateOfStartOfFinancialYear><in-capmkt:DateOfEndOfFinancialYear contextRef="OneD">2027-03-31</in-capmkt:DateOfEndOfFinancialYear><in-capmkt:DateOfBoardMeetingWhenFinancialResultsWereApproved contextRef="OneD">2026-07-29</in-capmkt:DateOfBoardMeetingWhenFinancialResultsWereApproved><in-capmkt:DateOnWhichPriorIntimationOfTheMeetingForConsideringFinancialResultsWasInformedToTheExchange contextRef="OneD">2026-07-15</in-capmkt:DateOnWhichPriorIntimationOfTheMeetingForConsideringFinancialResultsWasInformedToTheExchange><in-capmkt:DescriptionOfPresentationCurrency contextRef="OneD">INR</in-capmkt:DescriptionOfPresentationCurrency><in-capmkt:LevelOfRounding contextRef="OneD">Lakhs</in-capmkt:LevelOfRounding><in-capmkt:TypeOfReportingPeriod contextRef="OneD">Quarterly</in-capmkt:TypeOfReportingPeriod><in-capmkt:ReportingQuarter contextRef="OneD">First quarter</in-capmkt:ReportingQuarter><in-capmkt:IsCompanyReportingMultisegmentOrSingleSegment contextRef="OneD">Single segment</in-capmkt:IsCompanyReportingMultisegmentOrSingleSegment><in-capmkt:DescriptionOfSingleSegment contextRef="OneD">PERSONAL CARE (Including Oral Care)</in-capmkt:DescriptionOfSingleSegment><in-capmkt:DateOfStartOfBoardMeeting contextRef="OneD">2026-07-29</in-capmkt:DateOfStartOfBoardMeeting><in-capmkt:StartTimeOfBoardMeeting contextRef="OneD">10:30:00</in-capmkt:StartTimeOfBoardMeeting><in-capmkt:DateOfEndOfBoardMeeting contextRef="OneD">2026-07-29</in-capmkt:DateOfEndOfBoardMeeting><in-capmkt:EndTimeOfBoardMeeting contextRef="OneD">11:30:00</in-capmkt:EndTimeOfBoardMeeting><in-capmkt:DeclarationOfUnmodifiedOpinionOrStatementOnImpactOfAuditQualification contextRef="OneD">Not applicable</in-capmkt:DeclarationOfUnmodifiedOpinionOrStatementOnImpactOfAuditQualification><in-capmkt:WhetherStatementOnDeviationOrVariationForProceedsOfPublicIssueOrRightIssueOrPreferentialIssueOrQIPEtcIsApplicableToTheCompanyForTheCurrentQuarter contextRef="OneD">false</in-capmkt:WhetherStatementOnDeviationOrVariationForProceedsOfPublicIssueOrRightIssueOrPreferentialIssueOrQIPEtcIsApplicableToTheCompanyForTheCurrentQuarter><in-capmkt:WhetherTheDisclosureForTheDefaultOnLoansAndDebtSecuritiesIsApplicableToTheEntity contextRef="OneD">false</in-capmkt:WhetherTheDisclosureForTheDefaultOnLoansAndDebtSecuritiesIsApplicableToTheEntity><in-capmkt:NoteForNonApplicabilityOfTheDisclosureForTheDefaultOnLoansAndDebtSecuritiesToTheEntity contextRef="OneD">Not 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unitRef="INR">0</in-capmkt:ShareOfProfitLossOfAssociatesAndJointVenturesAccountedForUsingEquityMethod><in-capmkt:ProfitLossForPeriod contextRef="OneD" decimals="-5" unitRef="INR">3430800000</in-capmkt:ProfitLossForPeriod><in-capmkt:OtherComprehensiveIncomeNetOfTaxes contextRef="OneD" decimals="-5" unitRef="INR">0</in-capmkt:OtherComprehensiveIncomeNetOfTaxes><in-capmkt:ComprehensiveIncomeForThePeriod contextRef="OneD" decimals="-5" unitRef="INR">3430800000</in-capmkt:ComprehensiveIncomeForThePeriod><in-capmkt:PaidUpValueOfEquityShareCapital contextRef="OneD" decimals="-5" unitRef="INR">272000000</in-capmkt:PaidUpValueOfEquityShareCapital><in-capmkt:FaceValueOfEquityShareCapital contextRef="OneD" decimals="INF" unitRef="INRPerShare">1</in-capmkt:FaceValueOfEquityShareCapital><in-capmkt:BasicEarningsLossPerShareFromContinuingOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">12.61</in-capmkt:BasicEarningsLossPerShareFromContinuingOperations><in-capmkt:DilutedEarningsLossPerShareFromContinuingOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">12.61</in-capmkt:DilutedEarningsLossPerShareFromContinuingOperations><in-capmkt:BasicEarningsLossPerShareFromDiscontinuedOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">0</in-capmkt:BasicEarningsLossPerShareFromDiscontinuedOperations><in-capmkt:DilutedEarningsLossPerShareFromDiscontinuedOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">0</in-capmkt:DilutedEarningsLossPerShareFromDiscontinuedOperations><in-capmkt:BasicEarningsLossPerShareFromContinuingAndDiscontinuedOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">12.61</in-capmkt:BasicEarningsLossPerShareFromContinuingAndDiscontinuedOperations><in-capmkt:DilutedEarningsLossPerShareFromContinuingAndDiscontinuedOperations contextRef="OneD" decimals="INF" unitRef="INRPerShare">12.61</in-capmkt:DilutedEarningsLossPerShareFromContinuingAndDiscontinuedOperations><in-capmkt:DebtEquityRatio contextRef="OneD" decimals="INF" unitRef="pure">0</in-capmkt:DebtEquityRatio><in-capmkt:DebtServiceCoverageRatio contextRef="OneD" decimals="INF" unitRef="pure">0</in-capmkt:DebtServiceCoverageRatio><in-capmkt:InterestServiceCoverageRatio contextRef="OneD" decimals="INF" unitRef="pure">0</in-capmkt:InterestServiceCoverageRatio><in-capmkt:DisclosureOfNotesOnFinancialResultsExplanatoryTextBlock contextRef="OneD">1 Sales net of GST for the quarter ended June 30 2026 increased by 12 percent in comparison to corresponding period of the previous year &lt;br /&gt; 
2 Other income for the year ended March 31 2026 included interest on income tax refunds amounting to Rs 2178 Lakhs and Rs Nil for the quarter ended June 30 2026 March 31 2026 and June 30 2025 &lt;br /&gt; 
 &lt;br /&gt; 
3 Exceptional item for the quarter ended June 30 2026 and March 31 2026 includes severance and related expenses with respect to certain organisational changes of Rs 334 lakhs and Rs 1658 lakhs respectively &lt;br /&gt; 
 &lt;br /&gt; 
4 On November 21 2025 the Government of India notified four Labour Codes the New Labour Code consolidating the existing labour laws In accordance with Ind AS 19 Employee Benefits changes in employee benefit plans arising from legislative amendments are treated as plan amendments requiring immediate recognition of past service cost in the Statement of Profit and Loss Pursuant to the New Labour Code the Company has recognised a one-time increase in employee benefit expenses amounting to Rs Nil for the quarter ended June 30 2026 Rs Nil for the quarter ended March 31 2026 and Rs 839 lakhs for the year ended March 31 2026 The said amount has been disclosed as an exceptional item in the Statement of Profit and Loss for the year ended March 31 2026 &lt;br /&gt; 
 &lt;br /&gt; 
5 The Company has identified Personal Care including Oral Care as its only primary reportable segment in accordance with the requirements of Ind AS 108 Operating Segments Accordingly no separate segment information has been provided &lt;br /&gt; 
 &lt;br /&gt; 
6 The Company does not have any subsidiary or associate or joint venture entity for the quarter ended June 30 2026 and for the previous year &lt;br /&gt; 
 &lt;br /&gt; 
7 The figures of the quarter ended March 31 2026 are the balancing figures between audited figures in respect of the full financial year and the published year to date figures upto the third quarter of the respective financial year which were subjected to limited review &lt;br /&gt; 
 &lt;br /&gt; 
8 The Statutory Auditors have carried out a Limited Review of the Financial results of the quarter ended June 30 2026 as required under Regulation 33 of SEBI Listing Obligations and Disclosure Requirements Regulations 2015 &lt;br /&gt; 
 &lt;br /&gt; 
The above results have been reviewed by the Audit Committee and approved by the Board of Directors at their respective meetings held on July 29 2026 &lt;br /&gt; 
 &lt;br /&gt; 
The full text of Colgate releases is available in the Investors section of our website at wwwcolgatepalmolivecoin and is also available on wwwbseindiacom and wwwnseindiacom &lt;br /&gt; 
</in-capmkt:DisclosureOfNotesOnFinancialResultsExplanatoryTextBlock><in-capmkt:RemarksForDebtEquityRatio contextRef="OneD">1 Debt relates to Lease Liabilities only The Company does not have any debts or borrowings &lt;br /&gt; 
    &lt;br /&gt; 
    Debt Equity Ratio as per schedule III &lt;br /&gt; 
 &lt;br /&gt; 
    Debt Equity Ratio  is Total Debt divided by Shareholders Equity which equals to 4 percent &lt;br /&gt; 
 &lt;br /&gt; 
2 Debt Service Coverage Ratio is Earnings available for Debt Service or Debt Service which equals to 237 times &lt;br /&gt; 
 &lt;br /&gt; 
3 Interest Service Coverage Ratio is EBIT divided by Interest which equals to 432 times &lt;br /&gt; 
 &lt;br /&gt; 
Interest cost on leases which are part of Lease Liabilties in the Financial Statements as per IndAS 116 &lt;br /&gt; 
adoption is disclosed as Finance Cost in the results The Company does not have any debts or borrowings &lt;br /&gt; 
 &lt;br /&gt; 
All the above mentioned figures are for the period April 26 to June 26</in-capmkt:RemarksForDebtEquityRatio><in-capmkt:RemarksForDebtServiceCoverageRatio contextRef="OneD">1 Debt relates to Lease Liabilities only The Company does not have any debts or borrowings &lt;br /&gt; 
    &lt;br /&gt; 
    Debt Equity Ratio as per schedule III &lt;br /&gt; 
 &lt;br /&gt; 
    Debt Equity Ratio  is Total Debt divided by Shareholders Equity which equals to 4 percent &lt;br /&gt; 
 &lt;br /&gt; 
2 Debt Service Coverage Ratio is Earnings available for Debt Service or Debt Service which equals to 237 times &lt;br /&gt; 
 &lt;br /&gt; 
3 Interest Service Coverage Ratio is EBIT divided by Interest which equals to 432 times &lt;br /&gt; 
 &lt;br /&gt; 
Interest cost on leases which are part of Lease Liabilties in the Financial Statements as per IndAS 116 &lt;br /&gt; 
adoption is disclosed as Finance Cost in the results The Company does not have any debts or borrowings &lt;br /&gt; 
 &lt;br /&gt; 
All the above mentioned figures are for the period April 26 to June 26</in-capmkt:RemarksForDebtServiceCoverageRatio><in-capmkt:RemarksForInterestServiceCoverageRatio contextRef="OneD">1 Debt relates to Lease Liabilities only The Company does not have any debts or borrowings &lt;br /&gt; 
    &lt;br /&gt; 
    Debt Equity Ratio as per schedule III &lt;br /&gt; 
 &lt;br /&gt; 
    Debt Equity Ratio  is Total Debt divided by Shareholders Equity which equals to 4 percent &lt;br /&gt; 
 &lt;br /&gt; 
2 Debt Service Coverage Ratio is Earnings available for Debt Service or Debt Service which equals to 237 times &lt;br /&gt; 
 &lt;br /&gt; 
3 Interest Service Coverage Ratio is EBIT divided by Interest which equals to 432 times &lt;br /&gt; 
 &lt;br /&gt; 
Interest cost on leases which are part of Lease Liabilties in the Financial Statements as per IndAS 116 &lt;br /&gt; 
adoption is disclosed as Finance Cost in the results The Company does not have any debts or borrowings &lt;br /&gt; 
 &lt;br /&gt; 
All the above mentioned figures are for the period April 26 to June 26</in-capmkt:RemarksForInterestServiceCoverageRatio><in-capmkt:DescriptionOfOtherExpenses contextRef="OneExpenses1D">Advertising</in-capmkt:DescriptionOfOtherExpenses><in-capmkt:OtherExpenses contextRef="OneExpenses1D" decimals="-5" unitRef="INR">2518600000</in-capmkt:OtherExpenses><in-capmkt:DescriptionOfOtherExpenses contextRef="OneExpenses2D">Others</in-capmkt:DescriptionOfOtherExpenses><in-capmkt:OtherExpenses contextRef="OneExpenses2D" decimals="-5" unitRef="INR">2576800000</in-capmkt:OtherExpenses><in-capmkt:DisclosureOfNotesOnSegmentsExplanatoryTextBlock contextRef="OneD">The Company has identified Personal Care  including Oral care as its only primary reportable segment in accordance with the requirements of Ind AS 108 Operating Segments Accordingly no seperate segment information has been provided</in-capmkt:DisclosureOfNotesOnSegmentsExplanatoryTextBlock><in-capmkt:IncomeTaxRelatingToItemsThatWillNotBeReclassifiedToProfitOrLoss contextRef="OneD" decimals="-5" unitRef="INR">0</in-capmkt:IncomeTaxRelatingToItemsThatWillNotBeReclassifiedToProfitOrLoss><in-capmkt:IncomeTaxRelatingToItemsThatWillBeReclassifiedToProfitOrLoss contextRef="OneD" decimals="-5" unitRef="INR">0</in-capmkt:IncomeTaxRelatingToItemsThatWillBeReclassifiedToProfitOrLoss><in-capmkt:OtherComprehensiveIncome contextRef="OneD" decimals="-5" unitRef="INR">0</in-capmkt:OtherComprehensiveIncome></xbrli:xbrl>